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A natural S-equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women. Use of soy protein supplement and resultant need for increased dose of levothyroxine.


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Several clinical trials , mostly in women with sufficient iodine intakes, have not found increased consumption of soy isoflavones to result in clinically significant changes in circulating thyroid hormone concentrations

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The ingestion of very high amount of tyramine may saturate the detoxification system and lead to clinical symptoms of intoxication. Effects of isoflavones on breast density in pre- and post-menopausal women:

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There has been little investigation regarding the potential effects of soy isoflavones in individuals with cognitive impairments Want to glance up her skirt? Molecular basis of the inhibition of human aromatase estrogen synthetase by flavone and isoflavone phytoestrogens: Messina M, Redmond G.
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  1. The specific role of isoflavones in reducing prostate cancer risk. A cross-sectional study of equol producer status and self-reported vasomotor symptoms.